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Mitsubishi Tanabe Pharma

2025-09-20T14:30:34Z

138.19.36.167:

{{Short description|Japanese pharmaceuticals company}}
{{More citations needed|date=June 2019}}
{{Infobox company
| name = Mitsubishi Tanabe Pharma Corporation
| logo = Mitsubishi Tanabe Pharma logo.jpg
| image = Mitsubishi Tanabe Pharma Corporation headquarter.jpg
| image_caption = Headquarters in Osaka
| type = [[Subsidiary]]
| industry = [[Pharmaceuticals]]
| fate = Tanabe Seiyaku Co., Ltd. merged with Mitsubishi Pharma to form Mitsubishi Tanabe Pharma
| predecessor = Neuroderm
| founded = {{Start date and age|1678}}<ref name="EXSERVAN">{{cite news|title=Mitsubishi Tanabe Pharma America Announces EXSERVAN (riluzole) is Now Available in the U.S. for the Treatment of ALS|url=https://www.biospace.com/article/releases/mitsubishi-tanabe-pharma-america-announces-exservan-riluzole-is-now-available-in-the-u-s-for-the-treatment-of-als/|date=30 June 2021|accessdate=10 May 2022|publisher=Genetic Engineering News}}</ref>
| parent = [[Mitsubishi Chemical Holdings Corporation]]
| location = Doshomachi, [[Osaka]]<ref name="EXSERVAN"/>
| hq_location_country = Japan
}}
'''Mitsubishi Tanabe Pharma Corporation''' is a Japanese [[pharmaceuticals]] company from Osaka,<ref name="EXSERVAN"/> a subsidiary of [[Mitsubishi Chemical Holdings Corporation]]. {{nihongo|'''Mitsubishi Pharma Corporation'''|三菱ウェルファーマ株式会社|Mitsubishi Werufāma Kabushiki-gaisha}} was formed in 2001 from the merger of Mitsubishi-Tokyo Pharmaceuticals and Welfide Corporation. On October 1, 2007, Tanabe Seiyaku Co., Ltd. merged with Mitsubishi Pharma to form Mitsubishi Tanabe Pharma.<ref>{{Cite web|url=https://www.mt-pharma.co.jp/e/company/history.html|title=Corporate History | About Us|website=Mitsubishi Tanabe Pharma Corporation}}</ref>

Originally founded in 1678, Mitsubishi Tanabe considers itself as one of the oldest pharmaceutical companies in the world.<ref name="EXSERVAN"/> Mitsubishi Tanabe Pharma is a member of the [[Mitsubishi UFJ Financial Group]] (MUFJ) [[keiretsu]].

==Products==
Mitsubishi-Tanabe Pharmaceuticals developed the first [[BET inhibitor]] molecules.<ref>{{cite patent |country=JP |number=2008156311}}</ref><ref>{{cite patent |country=JP |number=H0228181}}</ref>

In August 2014, the company announced three-year research collaboration agreement with [[AstraZeneca]] on [[diabetic nephropathy]], to replace dialysis or kidney transplantation.<ref name="AstraZenecaMTPC">{{cite news|title=AstraZeneca and MTPC come together for research on diabetic nephropathy drugs|url=http://www.genengnews.com/gen-news-highlights/astrazeneca-mtpc-partner-to-validate-diabetic-nephropathy-targets/81250258/?kwrd=Medicines%20Company|date=20 August 2014|accessdate=21 August 2014|publisher=Genetic Engineering News}}</ref>

An [[intravenous therapy|intravenous]] treatment of Mitsubishi Tanabe is Radicava (edaravone) which has the goal to slow the decline of physical function in patients with [[amyotrophic lateral sclerosis]] (ALS) and was approved by the U.S. [[Food and Drug Administration]] in 2017. The U.S. American branch of Mitsubishi Tanabe created a locator for healthcare and infusion centers.<ref name="ALS Care Centers">{{cite news|title=Mitsubishi Tanabe's revamped tool finds ALS care centers for patients|url=https://www.fiercepharma.com/marketing/mitsubishi-tanabe-opens-up-als-care-locator-platform-to-patients-and-caregivers|date=22 May 2019|accessdate=10 May 2022|publisher=Fierce Pharma|last=Snyder Bulik|first=Beth}}</ref>

Mitsubishe Tanabe has also an [[orally disintegrating tablet]] for ALS with Exservan ([[riluzole]]).<ref name="EXSERVAN"/>

==Ownership history==
In 1604, Tanabeya Matazaemon is granted a license by [[Tokugawa Ieyasu]] for trade in herbal medicines with [[Luzon]] and [[Ayutthaya Kingdom|Siam]].<ref>{{cite web |title=History of Mitsubishi Tanabe Pharma |url=https://www.mtpc-shiryokan.jp/en/history/ |website=Mitsubishi Tanabe Pharma Historical Museum |access-date=26 February 2022}}</ref>

In 1901, ''Motosaburo Tanabe, the Twelfth'' established a [[pharmacy]] in [[Tokyo]], which incorporated in 1921 as Motosaburo Tanabe Shoten.

In 1921, Nippon Tar Industries was established.

In 1940, Takeda Kasei Co., Ltd. was established by Chobei Takeda & Co., Ltd. (present-day [[Takeda Pharmaceutical Company]]) and Nippon Kasei Chemical Co. Ltd. (present-day [[Mitsubishi Chemical Corporation]]) and built its first plant in Higashi-Yoshitomi-mura, [[Fukuoka Prefecture]].

In 1943, Motosaburo Tanabe Shoten, changed its name to Tokyo Tanabe Pharmaceuticals Co., Ltd.

In 1946, Takeda Kasei Co., Ltd. changed its name to Yoshitomi Pharmaceutical Co., Ltd.

In 1949, Yoshitomi Pharmaceutical Co., Ltd. listed on Tokyo and Osaka stock exchanges.

In 1950, The Blood Plasma Corporation of Japan was established with head office and plant in [[Osaka]]. The founders included war criminals such as [[Masaji Kitano|Kitano Masaji]] who performed torture and experimentations on humans in the Japanese military's notorious [[Unit 731]] during World War II. These crimes were recognized by the UN as extreme "crimes against humanity".

In 1952, Nippon Tar Industries became Mitsubishi Chemical Industries, Ltd.

In 1964, Blood Plasma Corporation changed its name to [[Green Cross (Japan)|Green Cross Corporation]].

In 1998, Green Cross Corporation was acquired by Yoshitomi Pharmaceutical.

In 2000, Green Cross Corporation changing its name to Welfide Corporation.

In 1981, Mitsubishi Chemical Industries, Ltd. established a business alliance with Tokyo Tanabe Pharmaceuticals Co.

In 1984, Mitsubishi Chemical Industries, Ltd. changed its name to [[Mitsubishi Chemical Corporation]] following the merger with Mitsubishi Petrochemical Co., Ltd.

In 1999, Mitsubishi Chemical Corporation and Tokyo Tanabe Pharmaceuticals Co. merged formally and formed Mitsubishi-Tokyo Pharmaceuticals, Inc., to take over the combined pharmaceutical operations of the two companies.

In 2001, Mitsubishi-Tokyo Pharmaceuticals and Welfide Corporation merged to establish Mitsubishi Pharma Corporation, and Mitsubishi Tanabe Pharma.<ref>{{cite web |title=Family Tree of Mergers at Mitsubishi Tanabe Pharma |url=https://www.mtpc-shiryokan.jp/en/history/pdf/genealogy.pdf |website=Mitsubishi Tanabe Pharma Historical Museum |access-date=26 February 2022}}</ref>

In October 2005, Mitsubishi Pharma Corporation joined again with Mitsubishi Chemical Corporation to create [[Mitsubishi Chemical Holdings Corporation]].

In July, 2017, Mitsubishi Tanabe Pharma acquired Neuroderm for $1.1 billion.<ref>{{Cite news|url=http://uk.reuters.com/article/us-neuroderm-m-a-mitsub-tanabe-idUKKBN1A90IA|archive-url=https://web.archive.org/web/20170724064824/http://uk.reuters.com/article/us-neuroderm-m-a-mitsub-tanabe-idUKKBN1A90IA|url-status=dead|archive-date=July 24, 2017|title = Mitsubishi Tanabe Pharma to buy Israel's Neuroderm for $1.1 billion|newspaper = Reuters|date = 24 July 2017|last1 = Cohen|first1 = Sam Nussey}}</ref>

On 27 February 2020, Mitsubishi Tanabe Pharma was delisted from the Tokyo Stock Exchange, and is now described as a member of the Mitsubishi Chemical Holdings Group <ref>{{Cite web | url=https://www.mt-pharma.co.jp/e/release/nr/2020/pdf/e_MTPC200226.pdf | title=Announcement Concerning Delisting of the Company Shares | website=www.mt-pharma.co.jp}}</ref>

In February 2025, American private equity firm [[Bain Capital]] agreed to acquire Mitsubishi Tanabe Pharma for {{JPY|510|link=yes}} billion (US$3.4 billion).<ref>{{Cite news |last1=Bridge |first1=Anton |last2=Wu |first2=Kane |date=February 7, 2025 |title=Bain to buy Japan's Mitsubishi Tanabe Pharma for $3.4 billion |url=https://www.reuters.com/markets/deals/mitsubishi-chemical-sells-pharmaceuticals-subsidiary-bain-336-billion-deal-2025-02-07/ |publisher=Reuters}}</ref>

==References==
{{Reflist}}

==External links==
* [http://www.mt-pharma.co.jp/e/index.php Mitsubishi Tanabe Pharma] {{in lang|en}}
* {{cite web |url=https://www.mtpc-shiryokan.jp/en/ |title=Mitsubishi Tanabe Pharma Historical Museum }} {{in lang|en}}

{{Mitsubishi Chemical Holdings|state=autocollapse}}
{{Authority control}}

[[Category:Pharmaceutical companies of Japan]]
[[Category:Companies based in Osaka Prefecture]]
[[Category:Japanese companies established in 2007]]
[[Category:Pharmaceutical companies established in 2007]]
[[Category:Companies formerly listed on the Tokyo Stock Exchange]]
[[Category:Life sciences industry]]
[[Category:Mitsubishi companies]]
[[Category:Midori-kai]]
[[Category:Mitsubishi Chemical Holdings]]
[[Category:Announced mergers and acquisitions]]

Asakusa Shrine

2025-07-26T08:53:02Z

138.19.36.167: /* History */

{{Short description|Shinto shrine in Asakusa district, Tokyo, Japan}}
{{Infobox religious building
| name = Asakusa Shrine 浅草神社
| image = Asakusa shrine 2012.JPG
| caption =
| map_type = Japan
| map_alt =
| coordinates = {{coord|35|42|54.50|N|139|47|50.77|E|region:JP_type:landmark_scale:1000|display=title,inline}}
| map_relief =
| map_size =
| map_caption =
| religious_affiliation = [[Shinto]]
| type =
| deity = Hinokuma Hamanari Hinokuma Takenari Hajino Matsuchi<ref name="official site">{{cite web |url=http://www.asakusajinja.jp/english/ |title=Asakusa Shrine |accessdate=2019-02-04}}</ref> [[Ebisu (mythology)|Ebisu]]<ref>{{cite web |url=http://www.asakusa-e.com/ken/ken_e.htm |title=Asakusa Watch |accessdate=2008-03-07 |work=asakusa-e.com}}</ref>
| founded_by = [[Tokugawa Iemitsu]]
| established = 1649
| date_destroyed =
| location = 2-26-1, [[Asakusa]], [[Taitō, Tokyo|Taitō-ku]] [[Tokyo]] 111-0032
| website = {{URL|http://www.asakusajinja.jp/english/}}
| architecture_style = [[Ishinoma-zukuri|Gongen-zukuri]]
| festival =
| leadership =
}}

{{nihongo|'''Asakusa Shrine'''|浅草神社|Asakusa-jinja}} is a [[Shinto shrine]] in the [[Asakusa]] district of [[Tokyo]], [[Japan]]. Also known as {{nihongo|''Sanja-sama''||Shrine of the Three gods}}, it is one of the most famous Shinto shrines in the city.<ref name="mytravelguide">{{cite web |url=http://www.mytravelguide.com/attractions/profile-79065205-Japan_Tokyo_Asakusa_Shrine.html |title=Asakusa Shrine |accessdate=2008-03-07 |work=MyTravelGuide| archiveurl= https://web.archive.org/web/20080306000841/http://www.mytravelguide.com/attractions/profile-79065205-Japan_Tokyo_Asakusa_Shrine.html| archivedate= 6 March 2008 | url-status= live}}</ref>

The shrine honors the three men who founded the neighboring [[Sensō-ji]]. Part of a larger grouping of sacred buildings in the area, Asakusa Shrine is on the east side of the Sensō-ji, down a street marked by a large stone ''[[torii]]''. One of the only two buildings in the area to survive [[World War II]], it is designated an [[Important Cultural Properties of Japan|Important Cultural Property]] due to its long history.

==History==
[[File:Asakusa Shrine 2024.jpg|left|thumb|A ''[[torii]]'' marking the entrance to Asakusa Shrine]]

An example of the ''[[Ishi-no-ma-zukuri|gongen-zukuri]]'' style of architecture, Asakusa Shrine was commissioned by [[Tokugawa Iemitsu]] and built in 1649 during Japan's [[Edo period]].<ref name="japanguide">{{cite web |url=http://www.japan-guide.com/e/e3001.html |title=Sensoji |accessdate=2008-03-06| work=japan-guide.com| archiveurl= https://web.archive.org/web/20080306034657/http://www.japan-guide.com/e/e3001.html| archivedate= 6 March 2008 | url-status= live}}</ref> It was constructed to honor the three men who established and built the Sensō-ji.

Legend states that two brothers, fishermen named Hinokuma Hamanari and Hinokuma Takenari, found a [[Bodhisattva|bosatsu]] [[Kannon]] statuette caught in a fishing-net in the [[Sumida River]] on May 17, 628.<ref name="wgs">{{cite web |url= http://www.worldgreatestsites.com/sensoji.htm |title=Asakusa Kannon (Sensoji Temple) |accessdate=2008-03-06 |work=World Greatest Sites |archiveurl=https://web.archive.org/web/20080318103100/http://www.worldgreatestsites.com/sensoji.htm |archivedate=18 March 2008 |url-status=dead }}</ref> The third man, a wealthy landlord named Haji no Matsuchi<ref name="official site" /> (Haji no Nakatomo), heard about the discovery and approached the brothers to whom he delivered an impassioned sermon about the Buddha. The brothers were very impressed and subsequently converted to the Buddhist religion. The Kannon statue was consecrated in a small temple by the landlord and the brothers who thereafter devoted their lives to preaching the way of Buddhism.<ref name="official site" /> This temple is now known as the Sensō-ji. Asakusa Shrine was built in order to worship these men as deities.

The shrine and its surrounding area and buildings have also been the site of many Shinto and Buddhist festivals for centuries. The most important and famous of these festivals is [[Sanja Matsuri]], held in late May.

Unlike many other structures in the area, including the Sensō-ji, the shrine (along with the nearby Nitenmon gate to the Sensō-ji) survived the [[Bombing of Tokyo in World War II|Tokyo air raids of 1945]].<ref name="japanguide"/> Because of this rich history, it was designated an [[Important Cultural Properties of Japan|Important Cultural Property]] by the [[Government of Japan|Japanese Government]] in 1951.<ref>{{cite web |url=http://www.asakusajinja.jp/asakusajinja/syaden.html |script-title=ja:社殿について |accessdate=2008-03-21 |language=Japanese}}</ref>

Buildings in addition to the main shrine include a ''[[kagura-den]]'' (''[[kagura]]'' dance hall) and the Hikan Inari Shrine.

A Nishinomiya Inari shrine was once located near the [[Hōzōmon]] gate to Sensō-ji.<ref name=event>{{cite web |title=Event: Praying for Success in Business at Asakusa Hatsuka-Ebisu 2023 |first= |last= |date=23 January 2023 |url= https://everywhere.tokyo/en/event-asakusa-hatsuka-ebisu-2023/ |work=Tokyo Shitamachi Guide |publisher= |access-date=13 April 2024}}</ref><ref>McClain, James L., John M. Merriman, Kaoru Ugawa and Ugawa Kaoru. (1997). [https://books.google.com/books?id=-qOuykzxhKUC ''Edo and Paris: Urban Life and the State in the Early Modern Era.''] Ithaca: [[Cornell University Press]]. {{ISBN|978-0-8014-8183-3}}; [http://www.worldcat.org/wcpa/oclc/39088759 OCLC 39088759] [https://books.google.com/books?id=-qOuykzxhKUC&dq=Sensoji&pg=PA403 p. 403.]</ref> After the [[Government of Meiji Japan|Meiji government]] ordered the [[shinbutsu bunri|separation of Shinto and Buddhism]] in 1868, the Nishinomiya shrine became part of the Asakusa Shrine and was located near the ''kagura-den'', where it was destroyed in the 10 March 1945 firebombing.<ref name=event/>

==References==
{{Commons category|Asakusa shrine|Asakusa Shrine}}
{{Reflist}}

{{Shinto shrine}}
{{Authority control}}

[[Category:Asakusa]]
[[Category:Buildings and structures in Taitō]]
[[Category:Important Cultural Properties of Japan]]
[[Category:Ishi-no-ma-zukuri]]
[[Category:Shinbutsu bunri]]
[[Category:Shinto shrines in Tokyo]]

Ōsaka Namba Station

2025-07-09T02:26:41Z

138.19.36.167:

{{short description|Railway station in Osaka, Japan}}
{{for|other stations with a similar name|Namba Station (disambiguation)}}
{{Infobox station
| name = Osaka Namba Station
| native_name = 大阪難波駅
| native_name_lang = ja
| type =
| image = Osaka-Namba station.jpg
| alt =
| caption = Kintetsu Namba Building (Ōsaka Namba Station is located under this building)
| other_name =
| address = 4-1-17 Namba, [[Chūō-ku, Osaka]], [[Osaka Prefecture]]
| country = Japan
| coordinates = {{coord|34.667114|135.499142|format=dms|type:railwaystation_region:JP|display=inline,title}}
| map_type = Japan
| operator = {{Ublist
|[[Kintetsu Railway]]
|[[Hanshin Electric Railway]]
}}
| line = {{Plainlist|
* [[Kintetsu Namba Line]]
* [[Hanshin Namba Line]]
}}
| platforms =
| connections = Bus terminal
| structure =
| code = {{Colorbull|#{{rcr|Kintetsu|a}}}}A01 (Kintetsu) {{Colorbull|blue}}HS 41 (Hanshin)
| opened = March 15, 1970
| closed =
| former = Kintetsu Namba (until 2009)
| passengers =
| pass_year =
| services = {{adjstn
|system1=Kintetsu|line1=Namba
|through-left1=Hanshin Namba|type1={{SLL|Local|#03f|white}}{{SLL|Semi-Express|#093|black}}{{SLL|Suburban Semi-Express|#093|black}}{{SLL|Rapid Express|red|black}}|right1=Kintetsu Nippombashi
|type2={{SLL|Express|#ff8000|black}}|right2=Kintetsu Nippombashi
|type3={{SLL|Kintetsu Limited Express|red|black}}|right3=Ōsaka Uehommachi
|system4=Hanshin|line4=Namba
|through-left4=[[Kintetsu Namba Line]]|type4={{SLL|Local|#03f|white}}{{SLL|Semi-Express|#093|black}}{{SLL|Suburban Semi-Express|#093|black}}{{SLL|Rapid Express|red|black}}|right4=Sakuragawa}}
}}
{{Ōsaka Namba Station}}
{{nihongo|'''Ōsaka Namba Station'''|大阪難波駅|Ōsaka-Nanba-eki}} is a major railway station on the [[Kintetsu Namba Line]] and [[Hanshin Namba Line]] in the [[Namba]] district of [[Chūō-ku, Osaka]], Japan. It is adjacent to [[Namba Station]] and [[JR Namba Station]]. Trains of the [[Nara Line (Kintetsu)|Nara Line]] depart from and arrive at the station.

==Lines==
Ōsaka Namba Station is served by the following two lines.
* [[Kintetsu Namba Line]]
* [[Hanshin Namba Line]]

== Station layout ==
The station has an [[island platform]] and a [[side platform]] with three tracks on the third basement level, parallel to Namba Station on the Osaka Metro Sennichimae Line. There is a returning track in the west of the platforms between the two tracks of the Hanshin Namba Line.

===Platforms===
{{ja-rail-line|first=2|pfn=1, 2|name=Kintetsu Namba Line|idx=Kintetsu Namba Line, Nara Line|dir=for {{STN|Osaka Uehommachi|x}}, {{STN|Higashi-Hanazono|x}}, {{STN|Yamato-Saidaiji|x}} and {{STN|Kintetsu Nara|x||Nara}} for {{STN|Tenri|x}} / for {{STN|Kintetsu Nagoya|x||Nagoya}} / for {{STN|Kashikojima|x||Ise-Shima}}|col=#{{rcr|Kintetsu|a}}}}
{{ja-rail-line|first=3|pfn=3|name=Hanshin Namba Line|dir=for {{STN|Nishikujō|x}}, {{STN|Amagasaki|x|Hanshin}}, {{STN|Kōshien|x}}, and {{STN|Sannomiya|x||Kōbe Sannomiya}}|col=orange}}

== History ==
The station was first named {{nihongo|Kintetsu Namba Station|近鉄難波駅|Kintetsu-Nanba-eki}} on March 15, 1970, when Kintetsu's Namba Line opened.<ref>{{cite web|title=Kintetsu Corporation Company Profile|page=31|url=http://www.kintetsu.jp/english/pdf/kintetsu_english.pdf|accessdate=2009-03-25}}</ref> It was renamed to the present name on March 20, 2009, the date of opening of the Hanshin Namba Line.<ref>{{cite press release|script-title=ja:阪神なんば線開業に合わせ、「近鉄難波駅」を「大阪難波駅」に、「上本町駅」を「大阪上本町駅」に駅名変更します。|url=http://www.kintetsu.jp/news/files/ekimeihenkou%2020080331.pdf|trans-title="Kintetsu Namba Station" will be renamed "Ōsaka Namba Station", and "Uehommachi Station" will be "Ōsaka Uehommachi Station".|publisher=Kintetsu Corporation|date=March 31, 2008|language=Japanese}}</ref>

== Surrounding area ==
*Kintetsu Namba Building
*Midosuji Grand Building
*[[Dōtonbori]]
*[[Osaka City Air Terminal]] (OCAT)
*Minatomachi River Place (including [[FM OSAKA]])
*[[Namba Parks]], a shopping center and office complex

== References ==
{{reflist}}

{{Commonscat|Osaka-Namba Station}}
{{Kintetsu Nara Line}}
{{Hanshin Electric Railway Hanshin Namba Line}}
{{Osaka transit}}

{{DEFAULTSORT:Osaka Namba Station}}
[[Category:Chūō-ku, Osaka]]
[[Category:Railway stations in Osaka]]
[[Category:Stations of Kintetsu Railway]]
[[Category:Stations of Hanshin Electric Railway]]
[[Category:Railway stations in Japan opened in 1970]]