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		<title>Rastelli procedure</title>
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		<updated>2025-03-23T22:27:26Z</updated>

		<summary type="html">&lt;p&gt;2A00:23C5:FE1C:3701:E51F:4863:B203:DCAA: bad comma&lt;/p&gt;
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&lt;div&gt;{{short description|Open heart surgical procedure}}&lt;br /&gt;
{{More footnotes needed|date=July 2019}}&lt;br /&gt;
{{Infobox medical intervention&lt;br /&gt;
| name         = Rastelli procedure&lt;br /&gt;
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| specialty    = Cardiology&lt;br /&gt;
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The &#039;&#039;&#039;Rastelli procedure&#039;&#039;&#039; is an [[open heart surgery|open heart]] [[surgical]] procedure developed by [[Italian people|Italian]] [[physician]] and [[human heart|cardiac]] surgery [[research]]er [[Giancarlo Rastelli]], in 1967 at the [[Mayo Clinic]], and involves using a pulmonary or aortic homograft conduit to relieve pulmonary&lt;br /&gt;
obstruction in double outlet right ventricle with pulmonary stenosis.&amp;lt;ref&amp;gt;{{Cite journal|last1=Backer|first1=Carl Lewis|last2=Mavroudis|first2=Constantine|date=2003-08-01|title=The Rastelli Operation|url=https://www.optechtcs.com/article/S1522-2942(03)80012-0/abstract|journal=Operative Techniques in Thoracic and Cardiovascular Surgery|language=English|volume=8|issue=3|pages=121–130|doi=10.1053/S1522-2942(03)00034-7|issn=1522-2942|doi-access=free}}&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
On July 26, 1968, the first successful surgery was carried out at the Mayo Clinic by Dr. Robert Wallace.&lt;br /&gt;
&lt;br /&gt;
==Usage==&lt;br /&gt;
It is used to correct certain combinations of [[congenital]] [[congenital heart defect|heart defects]] (&#039;&#039;&#039;CHD&#039;&#039;&#039;s):&lt;br /&gt;
# [[dextro-Transposition of the great arteries]] (&#039;&#039;&#039;d-TGA&#039;&#039;&#039;), &#039;&#039;or&#039;&#039; [[overriding aorta]], &#039;&#039;or&#039;&#039; [[double outlet right ventricle]] (&#039;&#039;&#039;DORV&#039;&#039;&#039;); &#039;&#039;&#039;&#039;&#039;and&#039;&#039;&#039;&#039;&#039;&lt;br /&gt;
# [[Ventricular septal defect]] (&#039;&#039;&#039;VSD&#039;&#039;&#039;); &#039;&#039;&#039;&#039;&#039;and&#039;&#039;&#039;&#039;&#039;&lt;br /&gt;
# [[Right ventricular outflow tract obstruction]] (&#039;&#039;&#039;RVOTO&#039;&#039;&#039;):&amp;lt;ref&amp;gt;{{Cite web|title=The Rastelli Procedure for Transposition of the Great Arteries|url=https://www.annalsthoracicsurgery.org/article/S0003-4975(09)00636-5/pdf}}&amp;lt;/ref&amp;gt;&lt;br /&gt;
::* [[pulmonary atresia]]; &#039;&#039;or&#039;&#039;&lt;br /&gt;
::* [[human lung|pulmonary]] [[stenosis]]; &#039;&#039;or&#039;&#039;&lt;br /&gt;
::* [[sub-|subpulmonary]] stenosis.&lt;br /&gt;
&lt;br /&gt;
==Timing==&lt;br /&gt;
The Rastelli procedure is typically performed between one and two years of age. Since d-TGA, overriding aorta and DORV are [[cyanotic heart defect]]s, the child is palliated with a [[Blalock–Thomas–Taussig shunt]] in the meantime.&lt;br /&gt;
&lt;br /&gt;
==Surgical method==&lt;br /&gt;
Oxygenated blood is directed from the [[left ventricle]] to the [[aorta]] using a [[Gore-Tex]] patch. The VSD is also sealed with the patch. The [[pulmonary valve]] is surgically closed.&lt;br /&gt;
&lt;br /&gt;
From the [[right ventricle]] to the [[pulmonary bifurcation]], a synthetic [[wikt:conduit|conduit]] and a valve are constructed, which lets oxygen depleted blood to flow into the lungs for reoxygenation.&amp;lt;ref&amp;gt;{{Cite web|last=Tatco|first=Vincent|title=Rastelli procedure {{!}} Radiology Reference Article {{!}} Radiopaedia.org|url=https://radiopaedia.org/articles/rastelli-procedure|access-date=2021-12-16|website=Radiopaedia|language=en-US}}&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Results ==&lt;br /&gt;
In the last seven years of the study, there were seven early deaths (7%) and no surgical fatalities. Univariable analysis revealed that a straddling tricuspid valve (P =.04) and longer aortic crossclamping periods (P =.04) were risk factors for early mortality.&lt;br /&gt;
&lt;br /&gt;
There were 17 late deaths and a patient who had undergone heart transplantation after an average follow-up of 8.5 years.&lt;br /&gt;
&lt;br /&gt;
44 patients underwent reoperations for conduit [[stenosis]], 11 for left ventricular outflow tract obstruction and 28 for interventional [[catheter]]ization to alleviate conduit stenosis.&lt;br /&gt;
&lt;br /&gt;
There were nine patients with late arrhythmias and five patients who experienced sudden deaths.&lt;br /&gt;
&lt;br /&gt;
At 5, 10, 15 and 20 years, avoidance of death or transplantation (Kaplan-Meier) was 82 percent, 80 percent, 68 percent and 52 percent, respectively.&lt;br /&gt;
&lt;br /&gt;
At 5, 10 and 15 years of followup, the rates of death or reintervention (catheterization or surgical therapy) were 53 percent, 24 percent and 21 percent, respectively.&amp;lt;ref name=&amp;quot;:0&amp;quot;&amp;gt;{{Cite journal|last1=Kreutzer|first1=Christian|last2=Vive|first2=Julie De|last3=Oppido|first3=Guido|last4=Kreutzer|first4=Jacqueline|last5=Gauvreau|first5=Kimberlee|last6=Freed|first6=Michael|last7=Mayer|first7=John E.|last8=Jonas|first8=Richard|last9=Nido|first9=Pedro J. del|date=2000-08-01|title=Twenty-five–year experience with Rastelli repair for transposition of the great arteries|url=https://www.jtcvs.org/article/S0022-5223(00)44496-X/abstract|journal=The Journal of Thoracic and Cardiovascular Surgery|language=English|volume=120|issue=2|pages=211–223|doi=10.1067/mtc.2000.108163|pmid=10917934 |issn=0022-5223|doi-access=free}}&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Conclusions ==&lt;br /&gt;
Overall, the Rastelli procedure has a low initial fatality rate.&lt;br /&gt;
&lt;br /&gt;
Conduit blockage, left ventricular outflow tract obstruction and [[arrhythmia]], on the other hand, are linked to significant late morbidity and mortality.&amp;lt;ref name=&amp;quot;:0&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
Almost half of the patients who received the Rastelli operation required heart transplantation or died two decades later.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
{{reflist}}&lt;br /&gt;
* {{cite journal |last1=Rastelli |first1=G. C. |last2=McGoon |first2=D. C. |last3=Wallace |first3=R. B. |title=Anatomic correction of transposition of the great arteries with ventricular septal defect and subpulmonary stenosis |journal=[[The Journal of Thoracic and Cardiovascular Surgery]] |date=October 1969 |volume=58 |issue=4 |pages=545–552 |issn=0022-5223 |pmid=5387997 |doi=10.1016/s0022-5223(19)42568-3|doi-access=free }}&lt;br /&gt;
&lt;br /&gt;
{{Cardiac surgery procedures}}&lt;br /&gt;
&lt;br /&gt;
[[Category:Cardiac surgery]]&lt;br /&gt;
[[Category:Congenital heart defects]]&lt;/div&gt;</summary>
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