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Summary
DescriptionPicture2 aminotransferase.jpg
English: Ping Pong Bi Bi mechanism of PLP dependent enzyme catalyzed transamination. Aminotransferase reaction occurs in two stages consisting of three steps: Transamination, Tautomerisation and Hydolysis. In the first stage, alpha amino group of the aminoacid is transferred to PLP yielding an alpha ketoacid and PMP. In the second stage of the reaction, in which the amino group of PMP is transferred to a different alpha Ketoacid to yield a new alpha amino acid and PLP. Adopted from Lehninger, Principles of Biochemsitry
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