View source for Theophylline/ephedra/hydroxyzine

{{Short description|Drug used for treatment of asthma}}
{{Redirect|Marax|the demon also known as Marax|Morax (demon)}}
{{Infobox drug
| type              = combo
<!-- Combo data -->
| component1        = Theophylline
| class1            = [[Stimulant]]
| component2        = Ephedra (medicine)
| class2            = Stimulant
| component3        = Hydroxyzine
| class3            = [[Antihistamine]]
<!-- Clinical data -->
| pronounce         =
| tradename         = Marax
| Drugs.com         = {{Drugs.com|cons|marax}}
| MedlinePlus       =
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_AU_comment =
| pregnancy_category=
| routes_of_administration = [[Oral administration|By mouth]]
| ATCvet            =
| ATC_prefix        = R03
| ATC_suffix        = DA74
<!-- Legal status -->
| legal_AU          = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled -->
| legal_AU_comment  =
| legal_BR          = <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F -->
| legal_BR_comment  =
| legal_CA          = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_CA_comment  =
| legal_DE          = <!-- Anlage I, II, III or Unscheduled -->
| legal_DE_comment  =
| legal_NZ          = <!-- Class A, B, C -->
| legal_NZ_comment  =
| legal_UK          = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM / Class A, B, C -->
| legal_UK_comment  =
| legal_US          = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_US_comment  =
| legal_EU          =
| legal_EU_comment  =
| legal_UN          = <!-- N I, II, III, IV / P I, II, III, IV -->
| legal_UN_comment  =
| legal_status      = <!-- For countries not listed above -->
<!-- Identifiers -->
| CAS_number        = 64095-02-9
| PubChemSubstance  = 135272520
| DrugBank          =
| KEGG              =
}}

'''Theophylline/ephedra/hydroxyzine''' (trade name '''Marax''') is a drug that was used for the treatment of [[asthma]]. It was a combination of [[theophylline]], [[Ephedra (medicine)|ephedra]],<ref>{{cite book | vauthors = Hunt TM |title=Drug Games: The International Olympic Committee and the Politics of Doping, 1960–2008 |date=2011 |publisher=University of Texas Press |isbn=978-0-292-73957-4 |page=45 |url=https://books.google.com/books?id=E6QIYvAQMDUC |access-date=20 July 2018 |language=en}}</ref> and [[hydroxyzine]], and taken [[Oral administration|by mouth]].<ref>Marax {{Drugs.com|cons|marax}}. Accessed 23 April 2021.</ref><ref>{{cite journal | vauthors = Fixley M, Shen DD, Azarnoff DL | title = Theophylline bioavailability: a comparison of the oral absorption of a theophylline elixir and two combination theophylline tablets to intravenous aminophylline | journal = The American Review of Respiratory Disease | volume = 115 | issue = 6 | pages = 955–62 | date = June 1977 | pmid = 262107 | doi = 10.1164/arrd.1977.115.6.955 | doi-broken-date = 12 July 2025 }}</ref> It is no longer manufactured in the US due to approval of [[Ephedra (medicine)|ephedra]] being withdrawn by the [[Food and Drug Administration|FDA]].{{Citation needed|date=April 2021}}

==See also==
* [[Theophylline/ephedrine]]

== References ==
{{reflist}}

{{Drugs for obstructive airway diseases}}
{{Adenosine receptor modulators}}
{{Histamine receptor modulators}}
{{Monoamine releasing agents}}

[[Category:Bronchodilators]]
[[Category:Combination drugs]]

{{respiratory-system-drug-stub}}