4-AcO-DET

4-AcO-DET, also known as 4-acetoxy-N,N-diethyltryptamine as well as ethacetin or ethylacybin, is a psychedelic tryptamine.<ref name="TiHKAL" /> It was first synthesized in 1958 by Albert Hofmann in the Sandoz lab.<ref name="primer">Erowid 4-Acetoxy-DET Vaults : Primer. Accessed on April 19, 2007.</ref>

Use and effects

4-AcO-DET is orally active, and doses of 10 to 25Template:Nbspmg are common.<ref name="TiHKAL" /> Effects last 4 to 6Template:Nbsphours.<ref name="TiHKAL">{{#invoke:citation/CS1|citation |CitationClass=web }}</ref> The free base is also active when smoked in a dose range of 5 to 20Template:Nbspmg.<ref name="primer"/> Smoking 4-AcO-DET greatly speeds up the onset; peak effects are experienced within 10Template:Nbspminutes, and are usually over within 1 hour.Template:Specify

Pharmacology

It is expected that 4-AcO-DET is quickly hydrolyzed into the free phenolic 4-HO-DET by serum esterases, but human studies concerning the metabolic fate of this drug are lacking.<ref name="TiHKAL" />

Chemistry

Analogues

Analogues of 4-AcO-DET include diethyltryptamine (DET), 4-HO-DET (ethocin), ethocybin (4-PO-DET]]), 4-AcO-DMT (psilacetin), 4-AcO-DPT, 4-AcO-MET, and 4-AcO-MPT, among others.

Society and culture

Legal status

Sweden

Sveriges riksdags health ministry Statens folkhälsoinstitut classified 4-AcO-DET as "health hazard" under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of Nov 1, 2005, in their regulation SFS 2005:733 listed as 4-acetoxi-N,N-dietyltryptamin (4-AcO-DET), making it illegal to sell or possess.<ref name="notisum">{{#invoke:citation/CS1|citation |CitationClass=web }}</ref>

See also

• Substituted tryptamine

External links

• 4-AcO-DET - Isomer Design
• 4-AcO-DET - PsychonautWiki
• 4-Acetoxy-DET - Erowid
• The Big & Dandy 4-AcO-DET Thread - Bluelight

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