Cytolysis

From Vero - Wikipedia
Jump to navigation Jump to search

Template:Short description Template:Infobox medical condition Template:One source

File:Osmotic pressure on blood cells diagram.svg
Blood cells in solutions with different osmotic pressure. Cytolysis would result in the image on the far right.
File:Human Erythrocytes OsmoticPressure PhaseContrast Plain.svg
Micrographs of osmotic pressure on red blood cells
File:White blood cell undergoing cytolysis, 2014-10-18.webm
A human white blood cell (upper right) in water swells until it bursts (at ~14 seconds)

Cytolysis, or osmotic lysis, occurs when a cell bursts due to an osmotic imbalance that has caused excess water to diffuse into the cell. Water can enter the cell by diffusion through the cell membrane or through selective membrane channels called aquaporins, which greatly facilitate the flow of water.<ref>Template:Cite book</ref> It occurs in a hypotonic environment, where water moves into the cell by osmosis and causes its volume to increase to the point where the volume exceeds the membrane's capacity and the cell bursts. The presence of a cell wall prevents the membrane from bursting, so cytolysis only occurs in animal and protozoa cells which do not have cell walls. The reverse process is plasmolysis.

In bacteria

Osmotic lysis would be expected to occur when bacterial cells are treated with a hypotonic solution with added lysozyme, which destroys the bacteria's cell walls.Template:Fact

Prevention

Different cells and organisms have adapted different ways of preventing cytolysis from occurring. For example, the paramecium uses a contractile vacuole, which rapidly pumps out excessive water to prevent the build-up of water and the otherwise subsequent lysis.<ref>Template:Cite book</ref>

See also

References

General references

Inline citations

Template:Reflist