Ependymin
Template:Short description Template:Cs1 config Template:Infobox protein Ependymin is a glycoprotein found in the cerebrospinal fluid of many teleost fish. The humans homolog is called ependymin related 1 that is encoded by the EPDR1 gene.
Ependymin is associated with the consolidation of long-term memory, possibly providing protection from strokes, and contributing to neuronal regeneration.<ref>Template:Cite journal</ref> This encoded protein was originally detected in elevated amounts of fluid within the central nervous system of teleost fishes.<ref>Template:Cite journal</ref> Along with long-term memory and neuronal regeneration, ependymin has been connected to specific aspects of changes in signaling within nerve cells leading to brain plasticity,<ref>Template:Cite journal</ref> as well as behavioral performance in response to environment stress in fishes.<ref>Template:Cite journal</ref> For example, this glycoprotein interaction in the extracellular matrix influences cell adhesion and migration processes in the central nervous system of teleost fishes.<ref>Template:Cite journal</ref> The presence of ependymin-related proteins can be found in both vertebrates and invertebrates.<ref name=":0">Template:Cite journal</ref> They have variety of functional roles in non-neural sites of organisms.<ref name=":0" /> For example, an ependymin-related gene that is upregulated in colon cancer known as UCC1 was found in human colorectal tumor cells.<ref>Template:Cite journal</ref>