Psammoma body
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A psammoma body is a round collection of calcium, seen microscopically. The term is derived Template:Ety.
Cause
Psammoma bodies are associated with the papillary (nipple-like) histomorphology and are thought to arise from,
- Infarction and calcification of papillae tips.
- Calcification of intralymphatic tumor thrombi.<ref>Template:Cite journal</ref>
Association with lesions
Psammoma bodies are commonly seen in certain tumors such as:
- Papillary thyroid carcinoma<ref>Chapter 20 in: Template:Cite book 8th edition.</ref>
- Papillary renal cell carcinoma<ref>{{#invoke:citation/CS1|citation
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- Ovarian papillary serous cystadenoma and cystadenocarcinoma<ref>Ovarian papillary serous cystadenocarcinoma at WebPath, The Internet Pathology Laboratory for Medical Education at Mercer University School of Medicine. Retrieved July 2011</ref>
- Endometrial adenocarcinomas (papillary serous carcinoma ~3%-4%)
- Meningiomas, in the central nervous system<ref>{{#invoke:citation/CS1|citation
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- Peritoneal and pleural mesothelioma
- Somatostatinoma (pancreas)<ref>Template:Cite journal</ref>
- Prolactinoma of the pituitary <ref>Robbin's Pathology, Eight Ed</ref>
- Glucagonoma<ref>{{#invoke:citation/CS1|citation
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- Micropapillary subtype of lung adenocarcinoma<ref>Template:Cite journal</ref>
Benign lesions
Psammoma bodies may be seen in:
- Endosalpingiosis<ref name=pmid1774734>Template:Cite journal</ref>
- Psammomatous melanotic schwannoma
- Melanocytic nevus<ref>Rapini, Ronald. Practical Dermatopathology. Elsevier Mosby, 2005, p. 10.</ref>
Appearance
Psammoma bodies usually have a laminar appearance, are circular, acellular and basophilic.
References
External links
Template:Sister project Slides:
