Timeline of medicine and medical technology
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Template:Short description Template:Use dmy dates This is a timeline of the history of medicine and medical technology.Template:Efn
Antiquity
- c. 12000 BC – The earliest known example of dental caries manipulation is found in a Paleolithic man in Northern Italy.<ref>Template:Cite journal</ref>
- 7300 - 6200 BC – First evidence of trepanation, with signs of healing suggesting survival, identified in a skull in Ukraine.<ref>Template:Cite journal</ref>
- 3350 - 3105 BC - Ötzi dies with a parasitic whipworm infection while carrying Piptoporus betulinus, a type of birch fungus that contains toxic resins against whipworm and induces diarrhea. It was likely used an anthelmintic medication.<ref>{{#invoke:citation/CS1|citation
|CitationClass=web }}</ref>
- 3000 BC – The origins of Ayurveda have been traced back to around 3,000 BCE.<ref name="book9781464967566">Template:Cite book</ref>
- c. 2600 BC – Imhotep the priest-physician who was later deified as the Egyptian god of medicine.<ref name="MagillAves1998" /><ref>{{#invoke:citation/CS1|citation
|CitationClass=web }}</ref>
- 2500 BC – Iry Egyptian inscription speaks of Iry as eye-doctor of the palace, palace physician of the belly, guardian of the royal bowels, and he who prepares the important medicine (name cannot be translated) and knows the inner juices of the body.<ref name="Silverberg1967" />
- 1900–1600 BC Akkadian clay tablets on medicine survive primarily as copies from Ashurbanipal's library at Nineveh.<ref name="ColónColón1999" />
- 1800 BC – Code of Hammurabi sets out fees for surgeons and punishments for malpractice<ref name="Silverberg1967" />
- 1800 BC – Kahun Gynecological Papyrus
- 1600 BC – Hearst papyrus, coprotherapy and magic<ref name="Loudon2001" />
- 1551 BC – Ebers Papyrus, coprotherapy and magic<ref name="Longrigg1993" />
- 1500 BC – Saffron used as a medicine on the Aegean island of Thera in ancient Greece
- 1500 BC – Edwin Smith Papyrus, an Egyptian medical text and the oldest known surgical treatise (no true surgery) no magic<ref name="Silverberg1967" />
- 1300 BC – Brugsch Papyrus and London Medical Papyrus
- 1250 BC – Asklepios<ref name="Silverberg1967" />
- 9th century – Hesiod reports an ontological conception of disease via the Pandora myth. Disease has a "life" of its own but is of divine origin.<ref name="Loudon2001">Template:Cite book</ref>
- 8th century – Homer tells that Polydamna supplied the Greek forces besieging Troy with healing drugs. Homer also tells about battlefield surgery Idomeneus tells Nestor after Machaon had fallen: A surgeon who can cut out an arrow and heal the wound with his ointments is worth a regiment.<ref name="Silverberg1967" />
- 700 BC – Cnidos medical school; also one at Cos
- 500 BC – Darius I orders the restoration of the House of Life (First record of a (much older) medical school)<ref name="Silverberg1967" />Template:Rp
- 500 BC – Bian Que becomes the earliest physician known to use acupuncture and pulse diagnosis
- 500 BC – The Sushruta Samhita is published, laying the framework for Ayurvedic medicine, giving many surgical procedures for first time such as lithotomy, forehead flap rhinoplasty, otoplasty and many more.
- Template:Circa – Template:Circa – Empedocles four elements<ref name="Longrigg1993" />
- 500 BC – Pills were used. They were presumably invented so that measured amounts of a medicinal substance could be delivered to a patient.
- 510–430 BC – Alcmaeon of Croton scientific anatomic dissections. He studied the optic nerves and the brain, arguing that the brain was the seat of the senses and intelligence. He distinguished veins from the arteries and had at least vague understanding of the circulation of the blood.<ref name="Silverberg1967" /> Variously described by modern scholars as Father of Anatomy; Father of Physiology; Father of Embryology; Father of Psychology; Creator of Psychiatry; Founder of Gynecology; and as the Father of Medicine itself.<ref name="Harris1973">Template:Cite book</ref> There is little evidence to support the claims but he is, nonetheless, important.<ref name="Longrigg1993">Template:Cite book</ref><ref name="Magill2003">Template:Cite book</ref>
- fl. 425 BC – Diogenes of Apollonia<ref name="Longrigg1993" />
- Template:Circa – 425 BC – Herodotus tells us Egyptian doctors were specialists: Medicine is practiced among them on a plan of separation; each physician treats a single disorder, and no more. Thus the country swarms with medical practitioners, some undertaking to cure diseases of the eye, others of the head, others again of the teeth, others of the intestines, and some those which are not local.<ref name="Silverberg1967">Template:Cite book</ref>
- 496 – 405 BC – Sophocles "It is not a learned physician who sings incantations over pains which should be cured by cutting."<ref name="Carrick2001">Template:Cite book</ref>
- 420 BC – Hippocrates of Cos maintains that diseases have natural causes and puts forth the Hippocratic Oath. Origin of rational medicine.
Medicine after Hippocrates
- c. 400 BC – 1 BC – The Huangdi Neijing (Yellow Emperor's Classic of Internal Medicine) is published, laying the framework for traditional Chinese medicine
- 4th century BC – Philistion of Locri<ref name="Longrigg1993" /> Praxagoras distinguishes veins and arteries and determines only arteries pulse<ref name="Traver2002">Template:Cite book</ref>
- 375–295 BC – Diocles of Carystus<ref name="MagillAves1998">Template:Cite book</ref><ref name="Longrigg1993" /><ref name="Nutton2005" />
- 354 BC – Critobulus of Cos extracts an arrow from the eye of Phillip II, treating the loss of the eyeball without causing facial disfigurement.<ref>Philip II of Macedonia: Greater Than Alexander by Richard A. Gabriel, 2010, pg. 10</ref>
- 3rd century BC – Philinus of Cos founder of the Empiricist school. Herophilos and Erasistratus practice androtomy. (Dissecting live and dead human beings)
- 280 BC – Herophilus Dissection<ref name="Magill2003" /> studies the nervous system and distinguishes between sensory nerves and motor nerves and the brain. also the anatomy of the eye and medical terminology such as (in Latin translation "net like" becomes retiform/retina.<ref name="Longrigg1993" />
- 270 – Huangfu Mi writes the Zhēnjiǔ jiǎyǐ jīng (The ABC Compendium of Acupuncture), the first textbook focusing solely on acupuncture.
- 250 BC – Erasistratus studies the brain and distinguishes between the cerebrum and cerebellum physiology of the brain, heart and eyes, and in the vascular, nervous, respiratory and reproductive systems.
- 219 – Zhang Zhongjing publishes Shang Han Lun (On Cold Disease Damage).
- 200 BC – the Charaka Samhita uses a rational approach to the causes and cure of disease and uses objective methods of clinical examination
- 124 – 44 BC – Asclepiades of Bithynia<ref name="Magill2003" />
- 116 – 27 BC – Marcus Terentius Varro Prototypal germ theory of disease.<ref name="Adler2004">Template:Cite book</ref>
- 1st century AD – Rufus of Ephesus; Marcellinus a physician of the first century AD;<ref name="Longrigg1993" /> Numisianus<ref name="Harris1973" />
- 23 – 79 AD – Pliny the Elder writes Natural History
- Template:Circa – Template:Circa – Aulus Cornelius Celsus Medical encyclopedia<ref name="Celsus1837">Template:Cite book</ref>
- 50 – 70 AD – Pedanius Dioscorides writes De Materia Medica – a precursor of modern pharmacopoeias that was in use for almost 1600 years
- 2nd century AD Aretaeus of Cappadocia
- 98 – 138 AD – Soranus of Ephesus<ref name="Durant1993">Template:Cite book</ref>
- 129 – 216 AD – Galen – Clinical medicine based on observation and experience.<ref name="Nutton2005" /> The resulting tightly integrated and comprehensive system, offering a complete medical philosophy dominated medicine throughout the Middle Ages and until the beginning of the modern era.<ref name="Loudon2002" />
After Galen 200 AD
{{#invoke:Labelled list hatnote|labelledList|Main article|Main articles|Main page|Main pages}}
- Template:Floruit – Fabulla or Fabylla, medical writer<ref>Flemming 2007, p. 265.</ref>
- d. 260 – Gargilius Martialis, short Latin handbook on Medicines from Vegetables and Fruits<ref name="Nutton2005" />
- 4th century Magnus of Nisibis, Alexandrian doctor and professor book on urine<ref name="Prioreschi2001" />
- 325 – 400 – Oribasius 70 volume encyclopedia<ref name="ColónColón1999">Template:Cite book</ref>
- 362 – Julian orders xenones built, imitating Christian charity (proto hospitals)<ref name="Prioreschi2001" />
- 369 – Basil of Caesarea founded at Caesarea in Cappadocia an institution (hospital) called Basileias, with several buildings for patients, nurses, physicians, workshops, and schools<ref name="Durant1993" />
- 375 – Ephrem the Syrian opened a hospital at Edessa<ref name="Durant1993" /> They spread out and specialized nosocomia for the sick, brephotrophia for foundlings, orphanotrophia for orphans, ptochia for the poor, xenodochia for poor or infirm pilgrims, and gerontochia for the old.<ref name="Durant1993" />
- 400 – The first hospital in Latin Christendom was founded by Fabiola at Rome<ref name="Durant1993"/>
- 420 – Caelius Aurelianus a doctor from Sicca Veneria (El-Kef, Tunisia) handbook On Acute and Chronic Diseases in Latin.<ref name="Nutton2005" />
- 447 – Cassius Felix of Cirta (Constantine, Ksantina, Algeria), medical handbook drew on Greek sources, Methodist and Galenist in Latin<ref name="Nutton2005" />
- 480 – 547 Benedict of Nursia founder of "monastic medicine"<ref name="Prioreschi1996">Template:Cite book</ref>
- 484 – 590 – Flavius Magnus Aurelius Cassiodorus<ref name="Getz1998">Template:Cite book</ref>
- fl. 511 – 534 – Anthimus Greek: Ἄνθιμος<ref name="Albala2002">Template:Cite book</ref>
- 536 – Sergius of Reshaina (died 536) – A Christian theologian-physician who translated thirty-two of Galen's works into Syriac and wrote medical treatises of his own<ref name="Russell" />
- 525 – 605 – Alexander of Tralles<ref name="Prioreschi2001">Template:Cite book</ref> Alexander Trallianus
- 500 – 550 – Aetius of Amida Encyclopedia 4 books each divided into 4 sections<ref name="ColónColón1999" /><ref name="Prioreschi2001" />
- second half of 6th century building of xenodocheions/bimārestāns by the Nestorians under the Sasanians, would evolve into the complex secular "Islamic hospital", which combined lay practice and Galenic teaching<ref name="Russell">{{#invoke:citation/CS1|citation
|CitationClass=web }}</ref>
- 550 – 630 Stephanus of Athens<ref name="Nutton2005" /><ref name="Athens.)Dickson1998">Template:Cite book</ref>
- 560 – 636 – Isidore of Seville
- c. 620 Aaron of Alexandria Syriac . He wrote 30 books on medicine, the "Pandects". He was the first author in antiquity who mentioned the diseases of smallpox and measles<ref name="Riggs2012">Template:Cite book</ref> translated by Māsarjawaih a Syrian Jew and Physician, into Arabic about A. D. 683
- c. 630 – Paul of Aegina Encyclopedia in 7 books very detailed surgery used by Albucasis<ref name="Nutton2005">Template:Cite book</ref><ref name="Prioreschi2001" /><ref name="Pormann2004">Template:Cite book</ref>
- 790 – 869 – Leo Itrosophist also Mathematician or Philosopher wrote "Epitome of Medicine"
- c. 800 – 873 – Al-Kindi (Alkindus) De Gradibus
- 820 – Benedictine hospital founded, School of Salerno would grow around it<ref name="ColónColón1999" />
- d. 857 – Mesue the elder (Yūḥannā ibn Māsawayh) Syriac Christian<ref name="Loudon2002">Template:Cite book</ref>
- c. 830 – 870 – Hunayn ibn Ishaq (Johannitius) Syriac-speaking Christian also knew Greek and Arabic. Translator and author of several medical tracts.<ref name="Loudon2002" />
- c. 838 – 870 – Ali ibn Sahl Rabban al-Tabari, writes an encyclopedia of medicine in Arabic.<ref>Template:Cite book</ref>
- c. 910d – Ishaq ibn Hunayn
- 9th century – Yahya ibn Sarafyun a Syriac physician Johannes Serapion,<ref name="Loudon2002" /> Serapion the Elder
- c. 865 – 925 – Rhazes pediatrics,<ref name="ColónColón1999" /><ref name=Tschanz>David W. Tschanz, PhD (2003), "Arab Roots of European Medicine", Heart Views 4 (2).</ref> and makes the first clear distinction between smallpox and measles in his al-Hawi.
- d. 955 – Isaac Judaeus Isḥāq ibn Sulaymān al-Isrāʾīlī Egyptian born Jewish physician<ref name="Loudon2002" />
- 913 – 982 – Shabbethai Donnolo alleged founding father of School of Salerno wrote in Hebrew<ref name="GraetzBloch1894">Template:Cite book</ref>
- d. 982 – 994 – 'Ali ibn al-'Abbas al-Majusi Haly Abbas<ref name="ColónColón1999" />
- 1000 – Albucasis (936–1018) surgery Kitab al-Tasrif, surgical instruments.<ref name="Loudon2002" />
- d. 1075 – Ibn Butlan Christian physician of Baghdad Tacuinum sanitatis the Arabic original and most of the Latin copies, are in tabular format<ref name="Loudon2002" />
- 1018 – 1087 – Michael Psellos or Psellus a Byzantine monk, writer, philosopher, politician and historian. several books on medicine<ref name="Prioreschi2001" />
- c. 1030 – Avicenna The Canon of Medicine The Canon remains a standard textbook in Muslim and European universities until the 18th century.
- c. 1071 – 1078 – Simeon Seth or Symeon Seth an 11th-century Jewish Byzantine translated Arabic works into Greek<ref name="Prioreschi2001" />
- 1084 – First documented hospital in England Canterbury<ref name="Durant1993" />
- d. 1087 – Constantine the African<ref name="Loudon2002" />
- 1083 – 1153 – Anna Komnene, Latinized as Comnena
- 1095 – Congregation of the Antonines, was founded to treat victims of "St. Anthony's fire" a skin disease.<ref name="Durant1993" />
- Late 11th or early 12th century – Trotula<ref name="Schulman2002">Template:Cite book</ref>
- 1123 – St Bartholomew's Hospital founded by the court jester Rahere Augustine nuns originally cared for the patients. Mental patients were accepted along with others<ref name="HowellsOsborn1984">Template:Cite book</ref>
- 1127 – Stephen of Antioch translated the work of Haly Abbas
- 1100 – 1161 – Avenzoar Teacher of Averroes<ref name="O'Leary1939">Template:Cite book</ref>
- 1170 – Rogerius Salernitanus composed his Chirurgia also known as The Surgery of Roger
- 1126 – 1198 – Averroes<ref name="ColónColón1999" />
- d. c. 1161 – Matthaeus Platearius
1200–1499
- 1203 – Innocent III organized the hospital of Santo Spirito at Rome inspiring others all over Europe
- c. 1210 – 1277 – William of Saliceto, also known as Guilielmus de Saliceto
- 1210 – 1295 – Taddeo Alderotti – Scholastic medicine<ref name="French2003">Template:Cite book</ref>
- 1240 Bartholomeus Anglicus<ref name="Loudon2001" />
- 1242 – Ibn al-Nafis suggests that the right and left ventricles of the heart are separate and discovers the pulmonary circulation and coronary circulation<ref name="Loudon2002" />
- c. 1248 – Ibn al-Baytar wrote on botany and pharmacy,<ref name="Loudon2002" /> studied animal anatomy and medicine veterinary medicine.
- 1249 – Roger Bacon writes about convex lens spectacles for treating long-sightedness
- 1257 – 1316 Pietro d'Abano also known as Petrus De Apono or Aponensis<ref>Template:Cite book</ref>
- 1260 – Louis IX established Les Quinze-vingt; originally a retreat for the blind, it became a hospital for eye diseases, and is now one of the most important medical centers in Paris<ref name="Durant1993" />
- c. 1260 – 1320 Henri de Mondeville
- 1284 – Mansur hospital of Cairo<ref name="ColónColón1999" />
- Template:Circa – Template:Circa Joannes Zacharias Actuarius a Byzantine physician wrote the last great compendium of Byzantine medicine<ref name="Prioreschi2001" />
- 1275 –1326 – Mondino de Luzzi "Mundinus" carried out the first systematic human dissections since Herophilus of Chalcedon and Erasistratus of Ceos 1500 years earlier.<ref name="ZimmermanVeith1993" /><ref name="Crombie1959">Template:Cite book</ref>

Anathomia, 1541 - 1288 – The hospital of Santa Maria Nuova founded in Florence, it was strictly medical.<ref name="Loudon2001" />
- 1300 – concave lens spectacles to treat myopia developed in Italy.<ref>Vincent Ilardi, Renaissance Vision from Spectacles to Telescopes (Philadelphia, Pennsylvania: American Philosophical Society, 2007), page 5.</ref>
- 1310 – Pietro d'Abano's Conciliator (Template:Circa)<ref name="Loudon2001" />
- d. 1348 – Gentile da Foligno<ref name="French2003" />
- 1292–1350 – Ibn Qayyim al-Jawziya<ref name="ColónColón1999" />
- 1306–1390 – John of Arderne<ref name="ZimmermanVeith1993" /><ref name="ArderneMillar1922">Template:Cite book</ref><ref name="Arderne1999">Template:Cite book</ref>
- d. 1368 – Guy de Chauliac<ref name="ZimmermanVeith1993">Template:Cite book</ref><ref name="Chauliac)McVaugh1997">Template:Cite book</ref>
- f. 1460 – Heinrich von Pfolspeundt<ref name="ZimmermanVeith1993" /><ref name="Crombie1959" /><ref name="Grant1974">Template:Cite book</ref><ref name="McCallum2008">Template:Cite book</ref><ref name="BuckFund1917" />
- 1443 – 1502 – Antonio Benivieni<ref name="ZimmermanVeith1993" /><ref name="BenivieniPolybus1529">Template:Cite book</ref> Pathological anatomy<ref name="Thorndike1958">Template:Cite book</ref>
- 1493 – 1541 – Paracelsus<ref name="ZimmermanVeith1993" /> On the relationship between medicine and surgery<ref name="Pagel1958">Template:Cite book</ref> surgery book<ref name="Crone2004">Template:Cite book</ref>
1500–1799

- Early 16th century:
- Paracelsus, an alchemist by trade, rejects occultism and pioneers the use of chemicals and minerals in medicine. Burns the books of Avicenna, Galen and Hippocrates.<ref name="Hamilton1831">Template:Cite book</ref>
- Hieronymus Fabricius<ref name="ZimmermanVeith1993" /> His "Surgery" is mostly that of Celsus, Paul of Aegina, and Abulcasis citing them by name.<ref name="M.D.1895">Template:Cite book</ref>
- Caspar Stromayr<ref name="ZimmermanVeith1993" /><ref name="Schumpelick2000">Template:Cite book</ref>
- 1500? – 1561 Pierre Franco<ref name="ZimmermanVeith1993" /><ref name="BuckFund1917">Template:Cite book</ref><ref name="Barsky1964">Template:Cite journal</ref><ref name="FrancoRosenman2006">Template:Cite bookTemplate:Self-published source</ref>Template:Self-published inline
- Ambroise Paré (1510–1590) pioneered the treatment of gunshot wounds.<ref name="ZimmermanVeith1993" /><ref name="Paget1897">Template:Cite book</ref><ref name="ParéSpiegel1649">Template:Cite book</ref>
- Bartholomeo Maggi at Bologna, Felix Wurtz of Zurich, Léonard Botal in Paris, and the Englishman Thomas Gale (surgeon), (the diversity of their geographical origins attests to the widespread interest of surgeons in the problem), all published works urging similar treatment to Paré's. But it was Paré's writings which were the most influential.<ref name="Tallett1997">Template:Cite book</ref>
- 1518 – College of Physicians founded now known as Royal College of Physicians of London is a British professional body of doctors of general medicine and its subspecialties. It received the royal charter in 1518<ref name="WolfDannemann1935" />
- 1510 – 1590 – Ambroise Paré surgeon<ref name="WolfDannemann1935">Template:Cite book</ref>
- 1540 – 1604 – William Clowes<ref name="ZimmermanVeith1993" /><ref name="McCallum2008" /><ref name="Norton2008">Template:Cite book</ref> – Surgical chest for military surgeons<ref name="Norton2008" /><ref name="Ellis2001">Template:Cite book</ref>
- 1543 – Andreas Vesalius publishes De Fabrica Corporis Humani which corrects Greek medical errors and revolutionizes European medicine<ref name="Asling2010">Template:Cite book</ref><ref name="Vesalius1633">Template:Cite book</ref>
- 1546 – Girolamo Fracastoro proposes that epidemic diseases are caused by transferable seedlike entities
- 1550 – 1612 – Peter Lowe<ref name="ZimmermanVeith1993" /><ref name="Ellis2001" /><ref name="Finlayson1889">Template:Cite book</ref>
- 1553 – Miguel Servet describes the circulation of blood through the lungs.
- 1556 – Amato Lusitano describes venous valves in the Ázigos vein
- 1559 – Realdo Colombo describes the circulation of blood through the lungs in detail
- 1563 – Garcia de Orta founds tropical medicine with his treatise on Indian diseases and treatments
- 1570 – 1643 – John Woodall Ship surgeons used lemon juice to treat scurvy<ref name="Ellis2001" /> wrote "The Surgions Mate"<ref name="Woodall1617">Template:Cite book</ref>
- 1590 – Microscope was invented, which played a huge part in medical advancement
- 1596 – Li Shizhen publishes Běncǎo Gāngmù or Compendium of Materia Medica
- 1603 – Girolamo Fabrici studies leg veins and notices that they have valves which allow blood to flow only toward the heart
- 1621 – 1676 – Richard Wiseman<ref name="ZimmermanVeith1993" /><ref name="McCallum2008" /><ref name="Ellis2001" /><ref name="Longmore1891">Template:Cite book</ref><ref name="Wiseman1734">Template:Cite book</ref>
- 1628 – William Harvey explains the circulatory system in Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus
- 1683 – 1758 – Lorenz Heister<ref name="ZimmermanVeith1993" /><ref name="Ellis2001" /><ref name="Heister1763">Template:Cite book</ref>
- 1688 – 1752 – William Cheselden<ref name="ZimmermanVeith1993" /><ref name="Ellis2001" /><ref name="HoustounCheselden1723">Template:Cite book</ref><ref name="Cheselden2010">Template:Cite book</ref><ref name="Dran1768">Template:Cite book</ref>
- 1701 – Giacomo Pylarini gives the first smallpox inoculations in Europe. They were widely practised in the East before then.
- 1714 – 1789 – Percivall Pott<ref name="ZimmermanVeith1993" /><ref name="Pott(Sir.)1808">Template:Cite book</ref><ref name="PottEarle1819">Template:Cite book</ref><ref name="Mostof2005">Template:Cite book</ref><ref>Template:Cite book</ref>
- 1720 – Lady Mary Wortley Montagu
- 1728 – 1793 – John Hunter<ref name="ZimmermanVeith1993" /><ref>Template:Cite book</ref><ref name="Moore2005">Template:Cite book</ref><ref name="Londoncurator.)1993">Template:Cite book</ref>
- 1736 – Claudius Aymand performs the first successful appendectomy
- 1744 – 1795 – Pierre-Joseph Desault<ref name="ZimmermanVeith1993" /><ref name="Ellis2001" /><ref name="Desault1794">Template:Cite book</ref> First surgical periodical<ref name="Porter2001">Template:Cite book</ref>
- 1747 – James Lind discovers that citrus fruits prevent scurvy
- 1749 – 1806 – Benjamin Bell – Leading surgeon of his time and father of a surgical dynasty,<ref name="ZimmermanVeith1993" /> author of "A System of Surgery"<ref name="Bell2010">Template:Cite book</ref>
- 1752 – 1832 – Antonio Scarpa<ref name="ZimmermanVeith1993" /><ref name="Ellis2001" /><ref name="KingsnorthMajid2006">Template:Cite book</ref><ref name="Scarpa1808">Template:Cite book</ref>
- 1763 – 1820 – John Bell<ref name="ZimmermanVeith1993" /><ref name="McCallum2008" /><ref name="Garrison1921" /><ref name="Bell1808">Template:Cite book</ref>
- 1766 – 1842 – Dominique Jean Larrey Surgeon to Napoleon<ref name="ZimmermanVeith1993" /><ref name="McCallum2008" /><ref name="Ellis2001" /><ref name="M.D.Shuster2007">Template:Cite book</ref><ref name="Larrey1814">Template:Cite book</ref><ref name="(baron)Waller1815">Template:Cite book</ref><ref name="(baron)1861">Template:Cite book</ref>
- 1768 – 1843 – Astley Cooper surgeon<ref name="ZimmermanVeith1993" /><ref name="Ellis2001" /><ref name="KingsnorthMajid2006" /> lectures<ref name="bart.)1824">Template:Cite book</ref> principles and practice<ref name="CooperGreen1832">Template:Cite book</ref>
- 1774 – 1842 – Charles Bell, surgeon<ref name="ZimmermanVeith1993" /><ref name="McCallum2008" /><ref name="Garrison1921">Template:Cite book</ref><ref name="BellBell1827">Template:Cite book</ref>
- 1774 – Joseph Priestley discovers nitrous oxide, nitric oxide, ammonia, hydrogen chloride and oxygen
- 1777 – 1835 – Baron Guillaume Dupuytren<ref name="ZimmermanVeith1993" /> – Head surgeon at Hôtel-Dieu de Paris,<ref name="EatonSeegenschmiedt2012">Template:Cite book</ref> The age Dupuytren<ref name="Wylock2010">Template:Cite book</ref><ref name="Dupuytren1847">Template:Cite book</ref>
- 1785 – William Withering publishes "An Account of the Foxglove" the first systematic description of digitalis in treating dropsy
- 1790 – Samuel Hahnemann rages against the prevalent practice of bloodletting as a universal cure and founds homeopathy
- 1796 – Edward Jenner develops a smallpox vaccination method
- 1799 – Humphry Davy discovers the anesthetic properties of nitrous oxide
1800–1899
- 1800 – Humphry Davy announces the anaesthetic properties of nitrous oxide.
- 1803 – 1841 – Morphine was first isolated by Friedrich Sertürner, this is generally believed to be the first isolation of an active ingredient from a plant.
- 1813–1883 – James Marion Sims vesico-vaganial surgery<ref name="ZimmermanVeith1993" /><ref name="Rutkow1992">Template:Cite book</ref><ref name="Sims1886">Template:Cite book</ref> Father of surgical gynecology.<ref name="McCallum2008" /><ref name="Sims1888">Biography: Template:Cite book</ref>
- 1816 – René Laennec invents the stethoscope.
- 1827 – 1912 – Joseph Lister antiseptic surgery<ref name="ZimmermanVeith1993" /><ref name="Ellis2001" /><ref name="PasteurLister2008">Template:Cite book</ref> Father of modern surgery<ref name="Truax2010">Template:Cite book</ref>
- 1818 – James Blundell performs the first successful human transfusion.
- 1842 – Crawford Long performs the first surgical operation using anesthesia with ether.
- 1845 – John Hughes Bennett first describes leukemia as a blood disorder.
- 1846 – First painless surgery with general anesthetic.
- 1847 – Ignaz Semmelweis discovers how to prevent puerperal fever.
- 1849 – Elizabeth Blackwell is the first woman to gain a medical degree in the United States.
- 1850 – Female Medical College of Pennsylvania (later Woman's Medical College), the first medical college in the world to grant degrees to women, is founded in Philadelphia.<ref>"History of the Institution," Drexel University College of Medicine Legacy Center. Retrieved 25 June 2015.</ref>
- 1858 – Rudolf Carl Virchow 13 October 1821 – 5 September 1902 his theories of cellular pathology spelled the end of Humoral medicine.
- 1861 – Louis Pasteur discovers the Germ Theory
- 1867 – Lister publishes Antiseptic Principle of the Practice of Surgery, based partly on Pasteur's work.
- 1870 – Louis Pasteur and Robert Koch establish the germ theory of disease.
- 1878 – Ellis Reynolds Shipp graduates from the Women's Medical College of Pennsylvania and begins practice in Utah.
- 1879 – First vaccine for cholera.
- 1881 – Louis Pasteur develops an anthrax vaccine.
- 1882 – Louis Pasteur develops a rabies vaccine.
- 1887 – Willem Einthoven invents electrocardiography (ECG/EKG)<ref>Template:Cite journal</ref><ref>{{#invoke:citation/CS1|citation
|CitationClass=web }}</ref>
- 1890 – Emil von Behring discovers antitoxins and uses them to develop tetanus and diphtheria vaccines.
- 1895 – Wilhelm Conrad Röntgen discovers medical use of X-rays in medical imaging
1900–1999
- 1901 – Karl Landsteiner discovers the existence of different human blood types
- 1901 – Alois Alzheimer identifies the first case of what becomes known as Alzheimer's disease
- 1906 – Frederick Hopkins suggests the existence of vitamins and suggests that a lack of vitamins causes scurvy and rickets
- 1907 – Paul Ehrlich develops a chemotherapeutic cure for sleeping sickness
- 1907 – Henry Stanley Plummer develops the first structured patient record and clinical number (Mayo clinic)
- 1908 – Victor Horsley and R. Clarke invents the stereotactic method
- 1909 – First intrauterine device described by Richard Richter.<ref name="histcontraception">Template:Cite journal</ref>
- 1910 – Hans Christian Jacobaeus performs the first laparoscopy on humans
- 1917 – Julius Wagner-Jauregg discovers the malarial fever shock therapy for general paresis of the insane
- 1921 – Edward Mellanby discovers vitamin D and shows that its absence causes rickets
- 1921 – Frederick Banting and Charles Best discover insulin – important for the treatment of diabetes
- 1921 – Fidel Pagés pioneers epidural anesthesia
- 1923 – First vaccine for diphtheria
- 1924 – Hans Berger discovers human electroencephalography<ref>Template:Cite book</ref>
- 1926 – First vaccine for pertussis
- 1927 – First vaccine for tuberculosis
- 1927 – First vaccine for tetanus
- 1930 – First successful sex reassignment surgery performed on Lili Elbe in Dresden, Germany.
- 1932 – Gerhard Domagk develops a chemotherapeutic cure for streptococcus
- 1933 – Manfred Sakel discovers insulin shock therapy
- 1935 – Ladislas J. Meduna discovers metrazol shock therapy
- 1935 – First vaccine for yellow fever
- 1936 – Egas Moniz discovers prefrontal lobotomy for treating mental diseases; Enrique Finochietto develops the now ubiquitous self-retaining thoracic retractor
- 1938 – Ugo Cerletti and Lucio Bini discover electroconvulsive therapy
- 1938 – Howard Florey and Ernst Chain investigate Penicillin and attempted to mass-produce it and tested it on the policeman Albert Alexander (police officer) who recovered but died due to a lack of Penicillin
- 1943 – Willem J. Kolff builds the first dialysis machine
- 1944 – Disposable catheter – David S. Sheridan
- 1946 – Chemotherapy – Alfred G. Gilman and Louis S. Goodman
- 1947 – Defibrillator – Claude Beck
- 1948 – Acetaminophen – Julius Axelrod, Bernard Brodie
- 1949 – First implant of intraocular lens, by Sir Harold Ridley
- 1949 – Mechanical assistor for anesthesia – John Emerson
- 1952 – Jonas Salk develops the first polio vaccine (available in 1955)
- 1952 – Cloning – Robert Briggs and Thomas King
- 1953 – First live birth from frozen sperm
- 1953 – Heart-lung machine – John Heysham Gibbon
- 1953 – Medical ultrasonography – Inge Edler
- 1954 – Joseph Murray performs the first human kidney transplant (on identical twins)
- 1954 – Ventouse – Tage Malmstrom
- 1955 – Tetracycline – Lloyd Conover
- 1956 – Metered-dose inhaler – 3M
- 1957 – William Grey Walter invents the brain EEG topography (toposcope)
- 1958 – Pacemaker – Rune Elmqvist
- 1959 – In vitro fertilization – Min Chueh Chang
- 1960 – Invention of cardiopulmonary resuscitation (CPR)
- 1960 – First combined oral contraceptive approved by the FDA<ref name="histcontraception" />
- 1962 – Hip replacement – John Charnley
- 1962 – Beta blocker James W. Black
- 1962 – Albert Sabin develops first oral polio vaccine
- 1963 – Artificial heart – Paul Winchell
- 1963 – Thomas Starzl performs the first human liver transplant
- 1963 – James Hardy performs the first human lung transplant
- 1963 – Valium (diazepam) – Leo H. Sternbach
- 1964 – First vaccine for measles
- 1965 – Frank Pantridge installs the first portable defibrillator
- 1965 – First commercial ultrasound
- 1966 – C. Walton Lillehei performs the first human pancreas transplant
- 1966 – Rubella Vaccine – Harry Martin Meyer and Paul D. Parkman<ref>Template:Cite news</ref>
- 1967 – First vaccine for mumps
- 1967 – René Favaloro develops Coronary Bypass surgery
- 1967 – Christiaan Barnard performs the first human heart transplant
- 1968 – Powered prothesis – Samuel Alderson
- 1968 – Controlled drug delivery – Alejandro Zaffaron
- 1969 – Balloon catheter – Thomas Fogarty
- 1969 – Cochlear implant – William House
- 1970 – Cyclosporine, the first effective immunosuppressive drug is introduced in organ transplant practice
- 1971 – MMR Vaccine – developed by Maurice Hilleman
- 1971 – Genetically modified organisms – Ananda Chakrabart
- 1971 – Magnetic resonance imaging – Raymond Vahan Damadian
- 1971 – Computed tomography (CT or CAT Scan) – Godfrey Hounsfield
- 1971 – Transdermal patches – Alejandro Zaffaroni
- 1971 – Sir Godfrey Hounsfield invents the first commercial CT scanner
- 1972 – Insulin pump Dean Kamen
- 1973 – Laser eye surgery (LASIK) – Mani Lal Bhaumik
- 1974 – Liposuction – Giorgio Fischer
- 1976 – First commercial PET scanner
- 1978 – First live birth from in vitro fertilisation (IVF)
- 1978 – Last fatal case of smallpox<ref name="Pennington">Template:Cite journal</ref>
- 1979 – Antiviral drugs – George Hitchings and Gertrude Elion
- 1980 – Raymond Damadian builds first commercial MRI scanner
- 1980 – Lithotripter – Dornier Research Group
- 1980 – First vaccine for hepatitis B – Baruch Samuel Blumberg
- 1980 – Cloning of interferons – Sidney Pestka
- 1981 – Artificial skin – John F. Burke and Ioannis V. Yannas
- 1981 – Bruce Reitz performs the first human heart-lung combined transplant
- 1982 – Human insulin – Eli Lilly
- 1982 – Willem Johan Kolff performs the first artificial heart transplant.<ref>Template:Cite journal</ref>
- 1985 – Automated DNA sequencer – Leroy Hood and Lloyd Smith
- 1985 – Polymerase chain reaction (PCR) – Kary Mullis
- 1985 – Surgical robot – Yik San Kwoh
- 1985 – DNA fingerprinting – Alec Jeffreys
- 1985 – Capsule endoscopy – Tarun Mullick
- 1986 – Fluoxetine HCl – Eli Lilly and Co
- 1987 – commercially available Statins – Merck & Co.
- 1987 – Tissue engineering – Joseph Vacanti & Robert Langer
- 1988 – Intravascular stent – Julio Palmaz
- 1988 – Laser cataract surgery – Patricia Bath
- 1989 – Pre-implantation genetic diagnosis (PGD) – Alan Handyside
- 1989 – DNA microarray – Stephen Fodor
- 1990 – Gamow bag® – Igor Gamow
- 1992 – Description of Brugada syndrome (Pedro and Josep Brugada)
- 1992 – First vaccine for hepatitis A available<ref>{{#invoke:citation/CS1|citation
|CitationClass=web }}</ref>
- 1992 – Electroactive polymers (artificial muscle) – SRI International
- 1992 – Intracytoplasmic sperm injection (ICSI) – Andre van Steirteghem
- 1995 – Adult stem cell use in regeneration of tissues and organs in vivo – B. G Matapurkar U.S . International Patent
- 1996 – Dolly the Sheep cloned
- 1998 – Stem cell therapy – James Thomson
2000–2022
Template:Further Template:See also
- 2000 – The Human Genome Project draft was completed.
- 2001 – The first telesurgery was performed by Jacques Marescaux.
- 2003 – Carlo Urbani, of Doctors without Borders alerted the World Health Organization to the threat of the SARS virus, triggering the most effective response to an epidemic in history. Urbani succumbs to the disease himself in less than a month.
- 2005 – Jean-Michel Dubernard performs the first partial face transplant.
- 2006 – First HPV vaccine approved.
- 2006 – The second rotavirus vaccine approved (first was withdrawn).
- 2007 – The visual prosthetic (bionic eye) Argus II.
- 2008 – Laurent Lantieri performs the first full face transplant.
- 2011 – First successful Uterus transplant from a deceased donor in Turkey
- 2013 – The first kidney was grown in vitro in the U.S.
- 2013 – The first human liver was grown from stem cells in Japan.
- 2014 – A 3D printer is used for first ever skull transplant.
- 2014 - Sonendo, a medical technology company based in Laguna Hills, California, introduces the GentleWave system in the United States for root canal treatments.
- 2016 – The first ever artificial pancreas was created
- 2019 – 3D-print heart from human patient's cells.
- 2020 – First vaccine for COVID-19.
- 2022 – The complete human genome is sequenced.
See also
Notes
Citations
Template:Reflist Reference:
- 1. International patent USA. .wef 1995. US PTO no.6227202 and 20020007223.
- 2. R. Maingot's Text Book of Abdominal operations.1997 USA.
- 3. Text book of Obstetrics and Gynecology. 2010 J P Publishers.
References
Matapurkar B G. (1995). US international Patent 6227202 and 20020007223.medical use of Adult Stem cells. A new physiological phenomenon of Desired Metaplasia for regeneration of tissues and organs in vivo. Annals of NYAS 1998.
- Bynum, W. F. and Roy Porter, eds. Companion Encyclopedia of the History of Medicine (2 vol. 1997); 1840pp; 72 long essays by scholars excerpt and text search
- Conrad, Lawrence I. et al. The Western Medical Tradition: 800 BC to AD 1800 (1995); excerpt and text search
- Bynum, W.F. et al. The Western Medical Tradition: 1800–2000 (2006) excerpt and text search
- Loudon, Irvine, ed. Western Medicine: An Illustrated History (1997) online Template:Webarchive
- McGrew, Roderick. Encyclopedia of Medical History (1985)
- Template:Cite book
- Porter, Roy, ed. The Cambridge History of Medicine (2006); 416pp; excerpt and text search
- Porter, Roy, ed. The Cambridge Illustrated History of Medicine (2001) excerpt and text search excerpt and text search
- Singer, Charles, and E. Ashworth Underwood. A Short History of Medicine (2nd ed. 1962)
- Watts, Sheldon. Disease and Medicine in World History (2003), 166pp online Template:Webarchive
Further reading
External links
- Interactive timeline of medicine and medical technology (requires Flash plugin)
- The Historyscoper